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Could testosterone supplements delay cognitive decline?

Testosterone supplements have been found to improve cognitive function in older men, according to researchers at Edith Cowan University.

The researchers analysed the results of 14 randomised control trials, including one recently published in the American Journal of Geriatric Psychiatry, and are now calling for Australian men to volunteer for their own randomised control trial.

“As we age our brains gradually shrink, leading to a decline in memory, problem-solving and other cognitive functions,” said study co-author Associate Professor Hamid Sohrabi.

“This evidence shows that testosterone supplementation may help men stay mentally sharp into old age.”

The researchers say this finding could potentially lead to a way to delay the onset of dementia.

Lead researcher of the review, Professor Ralph Martins AO said: “If testosterone supplementation, either alone or in combination with other treatments, can delay the onset of symptoms of Alzheimer’s disease by a few years, this could make a huge difference to the lives of those with the disease and their families.”

The trial, set up by Professor Martins and Associate Professor Sohrabi, will test whether testosterone used on its own or in combination with fish oil can delay the cognitive decline associated with Alzheimer’s disease.

They are calling for male volunteers between 60 and 80 years old, without major medical conditions and who are not currently taking testosterone treatments, to take part in the study.

For more information about the trial or to volunteer, email Shane Fernandez at the Australian Alzheimer’s Research Foundation (WA) or phone (08) 6304 3966.

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